Cultivation of cotton using advanced technologies Bukhara Agrocluster LLC pays special attention to the introduction of intensive advanced technologies in the cultivation of cotton. In particular, with drip irrigation of agricultural crops in the fields of agricultural cluster farms, fertilizing with liquid fertilizers containing macro, meso and other microelements is widely used. Along with this, on the experimental site of the 4th branch of LLC “Bukhoro Service Agrocluster” on an area of 24 hectares, one can see the scale of work on the treatment with the preparation “Kafolon”, enriched with micro and meso elements of germination, which is an urgent issue in cotton processing. If, according to calculations, the efficiency of feeding plants with traditional fertilizers is 15-25%, then when feeding with new drugs "kafolon" its efficiency is achieved by 67%. The work carried out in these areas to fertilize cotton on the basis of the foliar feeding program of the BBCN system is showing its effectiveness. Before sowing, the seeds on the plots were treated with the "kafolon-seed treatment" preparation. At the subsequent stages of development of cotton, experts plan to use suspensions "kafolon-immunity", "kafolon-feed", "kafolon-finish" for their feeding, depending on their phenological development. Currently, on a large scale, work is being carried out on these areas on foliar feeding with a suspension of "kafolon-immunity" containing trace elements that reach inside the leaf and serve to increase endurance and prevent stress in cases where there is no fertilizer in the plant. The cotton plant fed with these new preparations is now intensively developing. The ongoing work on the implementation of this program, in turn, will increase the yield of cotton from each hectare to at least 40 centners Press service.